Dextromethorphan Pretreatment Does not Reduce the Tourniquet Pain in Normal Volunteers
نویسندگان
چکیده
منابع مشابه
Preoperative oral dextromethorphan does not reduce pain or morphine consumption after open cholecystectomy
BACKGROUND Dextromethorphan (DM), the D-isomer of the codeine analogue levorphanol, is a weak, noncompetitive N-Methyl-D-Aspartate (NMDA) receptor antagonist. It has been suggested that NMDA receptor antagonists induce preemptive analgesia when administrated before tissue injury occurs, thus decreasing the subsequent sensation of pain. METHOD The study was conducted in the Dr. Ali Shariati Ho...
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BACKGROUND Ondansetron, a serotonin-3 receptor antagonist, reduces postoperative shivering. Drugs that reduce shivering usually impair central thermoregulatory control, and may thus be useful for preventing shivering during induction of therapeutic hypothermia. We determined, therefore, whether ondansetron reduces the major autonomic thermoregulatory response thresholds (triggering core tempera...
متن کاملThe Effect of the Silicone Ring Tourniquet and Standard Pneumatic Tourniquet on the Motor Nerve Conduction, Pain and Grip Strength in Healthy Volunteers
Background: The pneumatic tourniquet (PT) is routinely used in upper and lower limb operations by most orthopaedic surgeons. The silicone ring tourniquet (SRT) was introduced in clinical practice the last decade. Clinical as well comparative studies in volunteers concerning its safety and efficacy have been published. The aim of this study was to investigate the postoperative effect of the si...
متن کاملPreemptive Analgesia Does Not Reduce Pain or Improve Postoperative Functioning
OBJECTIVES To examine the effectiveness of preemptive analgesia in gynecologic laparoscopy patients. METHODS A double-blinded, randomized trial was performed from June 2000 to June 2001. Preoperatively, patients were randomly assigned to 0.25% bupivicaine or normal saline control. Following anesthetic induction, the study drug or a placebo was injected prior to the proposed incisions. RESUL...
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BACKGROUND Persistent incisional pain is common after cardiac surgery and is believed to be in part related to inflammation and poorly controlled acute pain. Methylprednisolone is a corticosteroid with substantial antiinflammatory and analgesic properties and is thus likely to ameliorate persistent surgical pain. Therefore, the authors tested the primary hypothesis that patients randomized to m...
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ژورنال
عنوان ژورنال: Korean Journal of Anesthesiology
سال: 2000
ISSN: 0302-5780
DOI: 10.4097/kjae.2000.39.2.153